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We found anti-nuclear antibodies(ANA)in 26.7%of 150 relapsing-remitting and in 30.4%of 23 chronic progressive definite multiple sclerosis(MS) patients by retrospective chart review.These patients did not have systemic lupus erythematosus.Since ANA are not pathogenically relevant in MS,they are false-positive,and likely reflect systemic immune dysregulation in MS. |
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